Setup & Installation
Or with the ClawHub CLI, for registry-managed skill folders outside a full OpenClaw workspace:
What This Skill Does
Queries protein folding research data from Clarity Protocol, a community-driven database of protein mutation analyses run through AlphaFold2 via ColabFold. Returns variants filtered by disease or protein name, with confidence scores, UniProt identifiers, and fold IDs.
Directly queries a curated protein folding database with AlphaFold2 results, avoiding manual searches across UniProt or scattered literature.
When to use it
- Finding all folded mutations associated with Alzheimer's disease
- Looking up known variants for a specific protein like MAPT or APP
- Checking AlphaFold confidence scores for a particular mutation
- Retrieving fold IDs to pass into downstream analysis workflows
- Surveying available research data before starting a protein study
Example Workflow
Here's how your AI assistant might use this skill in practice.
User asks: What variants are available for the MAPT protein?
- 1Runs query_variants.py with --protein-name MAPT
- 2Paginates through results using next_cursor until exhausted
- 3Extracts variant notation, disease association, and average_confidence for each result
- 4Returns a structured list with fold IDs and confidence scores
A list of MAPT variants including mutation notation (e.g., P301L), associated disease, UniProt ID, AlphaFold confidence score, and fold ID
Requirements
Accounts, API keys, or tools you or your AI assistant may need to set up while using this skill.